Bipariden CAS 514-65-8 Anti-paralysis Agitans Drugs

Quick Details

Product Name: Bipariden 

Synonyms: BIPERIDEN (200 MG);1-(5-bicyclo[2.2.1]hept-2-enyl)-1-phenyl-3-(1-piperidyl)propan-1-ol;bipariden;1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-(1-piperidinyl)-1-propanol;1-Bicycloheptenyl-1-phenyl-3-piperidino-propanol-1;1-Piperidinepropanol, alpha-5-norbornen-2-yl-alpha-phenyl-;1-Piperidinepropanol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-;3-Piperidino-1-phenyl-1-bicyclo- 

CAS: 514-65-8 

MF: C21H29NO 

MW: 311.46106 

EINECS: 208-184-6 

Product Categories:  

Mol File: 514-65-8.mol 

Melting point  114°C 

Water Solubility  25.1 mg/L 

NIST Chemistry Reference Biperiden(514-65-8) 

Usage amoebicide 

Definition ChEBI: N-Propylpiperidine in which the methyl hydrogens are substituted by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all form of Parkinson's disease. 

Appearance:white powder 

Purity:99%

Package:1kg/foil bag or as your inquiry 

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Physical and Chemical Properties

The goods for the crystal. Melting_point 112-116 ° C (101 ° C). Not soluble in water, slightly soluble in ethanol, soluble in methanol. The goods hydrochloride (C21H29NO · HCI), also known as Anke spasm (Akineton, Akinophyl), as white crystals. About 275 ℃ decomposition, has also been reported Melting_point of 238 ℃.

Melting point: 114 ℃ Relative density: 1.126g / cm3 Solubility: 25.1 mg / L. Bipedilide Use of the goods for the anti-paralysis agitans drugs, antispasmodic drugs. The mice received oral LD50 of 545 mg / kg and intravenous injection of 56 mg / kg. The upstream raw material: cyclopentadiene

Indications for the treatment of paralysis agitans, drug-induced extrapyramidal syndrome

Consumption usage 1. tremor paralysis: oral 2mg each time, 3 to 4 times a day. 2. Drug-induced extrapyramidal syndrome: oral 2mg each time, 1 to 3 times a day, intramuscular or intravenous, adult 2 ~ 5mg, children per kilogram of body weight 0.04mg. If necessary, 30 minutes can be repeated intravenous 1, but not more than 4 times within 24 hours.

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