High Purity Steroid Powder Levobupivacaine Hydrochloride CAS No. 27262-48-2 

Basic Info

Product Name:Levobupivacaine Hydrochloride

Chemical Name:(s)-1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamidemonohydrochloride

CAS:27262-48-2

MF:C18H29ClN2O

MW:324.89

Model NO.: 27262-48-2

Suitable for: Elderly, Adult

Purity: >99%

Usage: Pain Killing

Shipping Way: TNT, EMS, FedEx, UPS, DHL

Quality Standard: Bp, USP, Ep, Cp

Trademark: Pharmlab

Certification: GMP, ISO 9001, USP, BP

Appearance: White crystalline powder

Payment Methods: Western Union, Money Gram, Bitcoin

Transport Package: Foil Bag, Drum or Carton or as your requirement

Origin: China

Purpose:This product is mainly used for epidural anesthesia.

Specification:

Description: White crystalline powder. 

Solubility: Freely soluble in water and in alcohol; slightly soluble 

in chloroform and in acetone. 

IdentifIcation A: By IR, To match with working standard 

B: By UV, To match with working standard 

C: Chloride test, To Matching with the standard 

PH 4.5 ~ 6.0 

Water 4.0%~6.0% 

Residue on ignition ≤ 0.1% 

Heavy metals ≤ 0.001% 

Limit of residual solvents Should be to match with the standard 

Chromatographic purity Should be to match with the standard 

(on the anhydrous basis.) 

Description：

Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.

Applications:

Levobupivacaine is the S-enantiomer of bupivacaine hydrochloride and is chemically described as (S)-1-butyl-2-piperidylformo-2', 6'-xylidide hydrochloride.

Levobupivacaine is a member of the amino amide class of local anaesthetics. It is indicated for surgical anesthesia and postoperative pain management.

The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.

Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.

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