Procaine Hydrochloride Procaine HCl Factory Supply anti-inflammatory Material

Procaine HCl Profile

Product name : Procaine Hydrochloride

Synonym: Aminocaine, anadolor, anesthesol, anestil, atoxicocaine, Benzoicacid,4-amino-,2-(diethylamino)ethylester,monohydrochloride, benzoicacid,p-amino-,2-(diethylamino)ethylester,monohydrochloride

Appearance: white crystalline powder

Purity: 99.9%

CAS: 51-05-8

Molecular formula: C13H21ClN2O2

Molecular weight:272.77

Melting point: 155-156 C(lit. )

Boiling point: 195-196 C 17mm

Flashing point: 195-196 C/17mm

Procaine HCl  Description

Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions, procaine is referred to generically as novocaine. It acts mainly as a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion-enhancing, and mood-enhancing effects.

For years procaine was used as a simple anesthetic, but soon researchers began to notice other curative powers of this substance.  Interest in experimentation ran so high that between 1930 and 1951, over 165 reports were published on the effects of procaine in the treatment of a variety of conditions including arthritis, neuralgia, itching, peptic ulcer, asthma and hypertension.  In the late 1940's three French physicians - Drs. Ghali, Boudon, and Guoit - found that procaine hydrochloride helped relieve suffering from asthma attacks.  Dr. Rene Leriche discovered that procaine injections were helpful in treating certain forms of arthritis, arteritis, and blood clots in the limbs.

Procaine HCl Application

Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.

Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.