99% Purity Antifungal Butenafine HCl CAS: 101827-46-7

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Product Name: Butenafine hydrochloride 

Synonyms: kp-363;n-((4-(1,1-dimethylethyl)phenyl)methyl)-n-methyl-1-naphthalenemethanaminehyd;n-((4-(1,1-dimethylethyl)phenyl)methyl)-n-methyl-1-naphthalenemethanaminhy;n-(4-tert-butylbenzyl)-n-methyl-1-naphthalenemethylamine hydrochloride;BUTENAFINE HCL;BUTENAFINE HYDROCHLORIDE;Butenafine hydrochloide;N-(4-t-Butylbenzyl)-N-Methyl-1-naphthalenemethylamine hydrochloride 

CAS: 101827-46-7 

MF: C23H27N.ClH 

MW: 353.93

Product Categories: Active Pharmaceutical Ingredients;Antifungals for Research and Experimental Use;Biochemistry;Butenafine;Amines;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API

Melting point  210-214°C 

Storage temp.  Refrigerator, Under Inert Atmosphere

Chemical Properties White Solid 

Usage Butenafine HCl is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase. 

Usage An antifungal, used to control dermal fungal infections such as athletes foot and ring worm. 

Standard:Enterprise Standard 

Price:negotiable 

MOQ:10g

Production Capacity:5000kg/month

Shipping: DHL, EMS, FedEx, UPS

Shelf life:2 years

More details pls contact:Whatapp:86 13048470428  

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Butenafine hydrochloride Description

Butenafine hydrochloride is a synthetic benzylamine antifungal, marketed under the trade names Mentax, Butop (India) and is the active ingredient in Lotrimin Ultra. It is structurally related to synthetic allylamine antifungals such as terbinafine .

Medical uses

Butenafine is indicated for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur, as well as athlete's foot (Tinea pedis), ringworm (Tinea corporis) and jock itch (Tinea cruris) due to Epidermophyton floccosum, Trichophyton mentagrophytes, Trichophyton rubrum, and Trichophyton tonsurans .

It also displays superior activity against Candida albicans than terbinafine and naftifine. Butenafine demonstrates low minimum inhibitory concentrations against Cryptococcus and Aspergillus.

There is some evidence that it is effective against dermatophyte infections of the toenails, but needs to be applied daily for prolonged periods (at least one year) .

Butenafine is typically available as a 1% topical cream .